Huntington-Whiteley has appeared in advertisements for Abercrombie & Fitch, Burberry, Bloomingdale's, Clinique, DKNY, French Connection, L.A.M.B., Pepe Jeans, Shiatzy Chen, Ralph Lauren, and Top Shop, among others. In 2008, she was also placed 6th on Harper's Bazaar's annual "Best Dressed List for 2008". The following year, Huntington-Whiteley received an Elle Style Award for 2009's "Model of the Year". She also starred in a provocative short film for Agent Provocateur playing a woman whose boyfriend forgets Valentine's Day, featured as the face of Karen Millen's Spring/Summer advertising campaign, and was photographed by Terry Richardson for 2010's Pirelli Calendar.
In April 2010, it was announced that Huntington-Whiteley would be the new face of Monsoon's Spring/Summer lingerie collection. Huntington-Whiteley and photographer Rankin will be working together to produce a book dedicated to her. Rosiex10, shot in California. She also appeared in a new series of Burberry ads for the company’s beauty line.